The fatty acids derived from sphingomyelin fractions of 10 rat and mouse tumors were examined quantitatively. All tumors, except a nontransplantable fibroadenoma, contained significant levels of a C‐24 dienoic acid which is absent from sphingomyelin of normal tissues or present in only trace amounts. The data suggest an abnormality in the metabolism of sphingolipids of tumor cells.
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Randall Wood (1974) studied this question.
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