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Assess how high-throughput sequencing and bioinformatic analysis of host small interfering RNA populations facilitate plant virus discovery, virome assembly, and antiviral defense characterization.

November 20, 2018Frontiers in MicrobiologyOpen Access

Small RNA-Omics for Plant Virus Identification, Virome Reconstruction, and Antiviral Defense Characterization

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Authors

MPMikhail M. PoogginCentre de Coopération Internationale en Recherche Agronomique pour le Développement

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Implication

Review reveals that small RNA profiling enables universal virus detection and virome reconstruction in plants, indicating robust applications for monitoring host antiviral immunity.

Key Points

Assess how high-throughput sequencing and bioinformatic analysis of host small interfering RNA populations facilitate plant virus discovery, virome assembly, and antiviral defense characterization.
Reviewed findings from studies analyzing natural and experimental viral infections across diverse cultivated and wild plant hosts.
Evaluated bioinformatics pipelines used to reconstruct complete viral and subviral genomes from deep-sequenced small interfering RNA libraries.
All land plant virus families, viral satellites, and viroids generate distinct small interfering RNAs capable of assembling into contigs long enough for complete virome identification.
Profiling small interfering RNA length, polarity, and hotspot maps successfully differentiates replicating episomal viruses from silent host genome-integrated endogenous viral elements.

Cite This Study

Mikhail M. Pooggin (2018) studied this question.

synapsesocial.com/papers/6a90821997989fa0aa8a41f8 https://doi.org/10.3389/fmicb.2018.02779

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Implication

Review reveals that small RNA profiling enables universal virus detection and virome reconstruction in plants, indicating robust applications for monitoring host antiviral immunity.

Small RNA-Omics for Plant Virus Identification, Virome Reconstruction, and Antiviral Defense Characterization

Discussion

Member takes

Implication

Key Points

Cite This Study

Small RNA-Omics for Plant Virus Identification, Virome Reconstruction, and Antiviral Defense Characterization

Discussion

Member takes

Implication

Key Points

Cite This Study

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