What question did this study set out to answer?

Investigate long-term mortality rates and overall life expectancy in patients diagnosed with Crohn's disease over 20 years earlier.

Long‐term prognosis in Crohn's disease: an epidemiological study of patients diagnosed more than 20 years ago in Cardiff

View Full Paper

Ask AI

Bookmark

Authors

Cohort study reveals elevated mortality risk in Crohn's disease, highlighting poorer long-term survival for individuals diagnosed at younger ages.

Investigate long-term mortality rates and overall life expectancy in patients diagnosed with Crohn's disease over 20 years earlier.
Traced 394 patients diagnosed with Crohn's disease prior to January 1, 1985, using a regional database established in 1934.
Determined mortality status as of December 31, 2004, calculating standardized mortality ratios (SMRs) and Kaplan-Meier age-at-death estimates.
The overall standardized mortality ratio was 1.29 (95% CI 1.12–1.45), which has remained stable without significant change since the 1970s.
SMR decreased significantly with age, falling from 16.95 (95% CI 14.99–18.91; 1 death) in patients aged 10–19 years to 0.92 (95% CI 0.65–1.19) in those older than 75 years.
Median age at death was 58 years for patients diagnosed between ages 10–26, 66 years for ages 27–52, 74 years for ages 53–58, and 79 years for ages 59 and older.

Canavan et al. (2006) studied this question.

View Full Paper

Ask AI

Bookmark

Cohort study reveals elevated mortality risk in Crohn's disease, highlighting poorer long-term survival for individuals diagnosed at younger ages.