Amyotrophic Lateral Sclerosis: Recent Research Trends

This book reports current research that may be important for understanding the etiology and therapy of amyotrophic lateral sclerosis (ALS). It is not meant as a review of what is known about ALS, and the reader will find very little to aid his understanding of the clinical disorder. The book focuses on the anterior horn cell of the spinal cord. The strength of the book is the excellent description of their own researches by investigators engaged in understanding the physiology and pathology of these cells. This, combined with an excellent bibliography, will be of great help to investigators who are studying or planning studies of the basic pathophysiology of amyotrophic lateral sclerosis. The initial chapters include an excellent review of the structural substrate of protein synthesis in the neurons as well as a discussion of the axonal transport systems. Motor neuron physiology and chemistry are discussed as they may possibly