Why the study?
The study was conducted to review the fundamentals, clinical role, and potential of selective perioperative intestinal decontamination for preventing postoperative wound complications and anastomosis insufficiency in colorectal surgery.
Does selective perioperative intestinal decontamination reduce the incidence of postoperative wound complications and anastomosis insufficiency in colorectal surgery?
Does selective perioperative intestinal decontamination reduce the incidence of postoperative wound complications and anastomosis insufficiency in colorectal surgery?
Selective perioperative intestinal decontamination may play a role in preventing postoperative wound complications and anastomosis insufficiency in colorectal surgery.
May reduce anastomotic complications in colorectal surgery; leaves open need for confirmatory RCTs.
The article provides a literary review of the fundamentals, role in clinical practice, and possibilities of selective perioperative intestinal decontamination. Aspects of prevention of postoperative wound complications and anastomosis insufficiency in colorectal surgery are analyzed. The key point is to reduce the number of certain bacterial strains that contribute to the development of exponential inflammation in the anastomosis zone. Modern schemes for the use of oral decontamination and their combination with intravenous antibiotic prophylaxis for the failure of anastomoses of the left half of the colon and rectum are considered.
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Михин et al. (2020) studied this question.
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