Light in the dark: Metal nanoparticles (M=Ag0, Au0, or Cu0) were electrodeposited onto ion-channel pores of a stable protein 1 membrane (see picture). The metal nanoparticles were implemented for detection of antigen–antibody binding events at the single-particle level using dark field microscopy and plasmon resonance Rayleigh scattering.
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Qin et al. (2011) studied this question.
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