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Discovery of 100-Å intermediate filaments in muscle; leaves open their role in cardiac cytoskeletal organization and requires prospective validation.
Early studies of skeletal muscle revealed the existence of two kinds of protein filaments: thick, ∼150 A–diameter myosin filaments and thin, ∼60 A–diameter actin filaments. These filaments combine to form myofibrils in developing and mature muscle cells. The year 1968 brought the discovery
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Laura Bonetta (2005) studied this question.
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