Virus Aetiology of Behcet's Syndrome

BEHSET (1937) described a muco-cutaneous-ocular syndrome characterized by recurrent uveitis and ulcers of the oral mucous membrane and external genitalia. Sezer (1953) reported the isolation of the causal virus from the subretinal fluid of affected eyes and later isolated the virus from the blood and urine of affected patients in the viraemia stage (Sezer, 1954). Beh9et (1939) and Ruggs-Gunn (1947) noted intracellular inclusion bodies in smears from buccal and genital aphthous ulcers, and Kozousek and Jandasek (1956) and Nakagawa and Shingu (1958) isolated the virus from the ocular fluids and genital aphthous ulcers of patients with Behret's disease.