A sensitive immunoperoxidase method employs a new chicken anti-B2-microglobulin (B2M) antibody for use on paraffin sections. The method demonstrates the loss of B2M from the cell membranes of malignant eccrine poromas , and this is correlated with the histopathologic and clinical criteria of malignancy.
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Colin A. Holden (1984) studied this question.
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