Article1 January 1966Encephalitis Associated with Herpes Simplex VirusWILLIAM E. RAWLS, M.D., PETER J. DYCK, M.D., DONALD W. KLASS, M.D., HUGH D. GREER III, M.D., ERNEST C. HERRMANN JR., PH.D.WILLIAM E. RAWLS, M.D., PETER J. DYCK, M.D., DONALD W. KLASS, M.D., HUGH D. GREER III, M.D., ERNEST C. HERRMANN JR., PH.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-1-104 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptFive patients with fatal encephalitis have come under our observation in a 2-year period. Herpes simplex virus was isolated from the brain in all of these cases. The neurologic picture could be separated into those features common to encephalitis and features related to focal cerebral hemisphere disturbance. The nonspecific symptoms consisted of headache, fever, nuchal rigidity, delirium, and coma. 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New Eng. J. Med. 271: 494, 1964. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: WILLIAM E. RAWLS, M.D.; PETER J. DYCK, M.D.; DONALD W. KLASS, M.D.; HUGH D. GREERIII, M.D.; ERNEST C. HERRMANNJR., PH.D.Affiliations: Rochester, MinnesotaFrom the Sections of Medicine, Neurology, Physiology, and Microbiology, Mayo Clinic and Mayo Foundation, Rochester, Minn.Dr. Rawls is presently Public Health Research Fellow, Department of Virology and Epidemiology, Baylor University College of Medicine, Houston, Tex.Requests for reprints should be addressed to Section of Publications, Mayo Clinic, Rochester, Minn. 55902. 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