Periodic Organic Psychosis Associated with Recurrent Herpes Simplex

RECURRENT herpes-simplex encephalitis has A never been proved in human beings although cases suggestive of it have been reported. It has been demonstrated in laboratory animals. This is a report of 17 episodes of an organic psychosis associated with recurrent herpes-simplex labialis.Case ReportA 9-year-old boy was well until June 28, 1959, when he became lethargic and vomited. His father noted 2 small pustules on the right side of the lower lip. On the following day fever, with swelling of the mouth, developed, and lesions appeared on both lips. These were diagnosed as herpes simplex. On July 31 he . . .