Why the study?
Does volume-for-volume replacement with appropriately composed solutions prevent acid-base equilibrium disturbances in surgical patients with gastrointestinal fluid losses?
Does volume-for-volume replacement with appropriately composed solutions prevent acid-base equilibrium disturbances in surgical patients with gastrointestinal fluid losses?
Volume-for-volume replacement of gastrointestinal fluid losses in surgery requires solutions of appropriate composition to avoid acid-base disturbances.
Answers are grounded in this paper and cite their sources.
Appropriately composed fluids may avoid acid-base disturbances in surgical GI losses; leaves open confirmation in prospective trials.
THE proper method for the replacement of gastrointestinal fluid losses in surgery has been the subject of considerable controversy. Volume-for-volume replacement with saline solution has been advocated, but the results have not justified the procedure. The use of glucose and saline mixtures as either equivalent or less than equivalent volume replacement has been equally unsuccessful.It is the purpose of this paper to demonstrate that volume-for-volume replacement of gastrointestinal losses does not lead to disturbances in acid–base equilibrium if replacement solutions of appropriate composition are used.The replacement of gastrointestinal losses is only a small part of complete parenteral fluid . . .
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Cooke et al. (1952) studied this question.
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