Immunocompromised patients with prolonged norovirus shedding can serve as reservoirs for nosocomial transmission, with transmission occurring weeks after initial diagnosis.
Prolonged shedding may enable late nosocomial transmission in immunocompromised patients; case report leaves open optimal isolation duration.
Norovirus (NoV) infection in immunocompromised patients may lead to prolonged norovirus shedding. Here, we demonstrate the involvement of three chronic shedders in hospital outbreaks. Combined epidemiological and molecular evidence suggests that in one case, NoV transmission occurred at least 17 days after the first diagnosis.
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Sukhrie et al. (2010) studied this question.
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