What question did this study set out to answer?

To assess common carotid intima-media thickness and identify associated clinical risk factors in patients presenting with acute ischemic stroke compared to matched controls.

January 1, 2009Neurology IndiaOpen Access

Common carotid intima-media thickness in acute ischemic stroke: A case control study

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Why the study?

Is carotid intima-media thickness increased in patients with acute ischemic stroke compared to matched controls?

Key Points

To assess common carotid intima-media thickness and identify associated clinical risk factors in patients presenting with acute ischemic stroke compared to matched controls.
Conducted a case-control study including 60 patients with CT-confirmed acute ischemic stroke (mean age 62 years, 63.3% male) and 50 controls matched for age, sex, diabetes, and hypertension.
Performed B-mode carotid duplex ultrasonography using a 7.5 MHz linear superficial array probe to quantify carotid intima-media thickness (CIMT) and detect carotid plaques.
Mean CIMT was significantly higher in patients with acute ischemic stroke (0.798 mm) compared to matched controls (0.600 mm; P < 0.0001).
Stroke patients with carotid plaques had significantly greater CIMT (0.95 ± 0.22 mm) than those without plaques (0.71 ± 0.12 mm; P < 0.001).
Carotid intima-media thickness differed significantly across age cohorts (P < 0.05) and showed an independent association with advancing age and plaque presence.

Structured PICO

Is carotid intima-media thickness increased in patients with acute ischemic stroke compared to matched controls?

Population

110 subjects: 60 patients with acute ischemic stroke diagnosed by CT scan (mean age 62 years, 63.3% male) and 50 controls matched by age, gender, diabetes, and hypertension.

Outcome

Average carotid intima-media thickness (CIMT) measured by carotid duplex scanningsurrogate

Carotid intima-media thickness is significantly increased in patients with acute ischemic stroke and is associated with increasing age and the presence of carotid plaques.

Discussion

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Implication

CIMT elevation was associated with acute ischemic stroke; case-control data leave open its incremental value for risk prediction.

Cite This Study

Sahoo et al. (2009) studied this question.

synapsesocial.com/papers/6a909d42b0770bec3fc7a72c https://doi.org/10.4103/0028-3886.57822

View Full Paper

Ask AI

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Common carotid intima-media thickness in acute ischemic stroke: A case control study

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Common carotid intima-media thickness in acute ischemic stroke: A case control study

Key Points

Structured PICO

Discussion

Implication

Cite This Study

Also Consider

Also Consider