Brominated Oxylipins and Oxylipin Glycosides from Red Sea Corals

Eight new brominated oxylipins 1−8, including two glycosides, were isolated from the Red Sea invertebrates Dendrophyllia sp., Dendronephthya sp. (red variety), Dendronephthya sp. (yellow variety), and Tubipora musica. Their structures were elucidated mainly on the basis of NMR spectroscopic data. The relative and absolute configurations were determined by analysis of NOESY and CD data and by the modified Mosher method. The compounds gave positive results in a brine shrimp toxicity assay, a sea urchin eggs test (Paracentrotus lividus), and a crown gall tumor on potato disks test (Agrobacterium tumefaciens). (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)