Why the study?
While the prognostic impact of severe right ventricular dysfunction is well understood, the added value of the right ventricular mechanical pattern regarding risk prediction in cardiac surgery remains unknown.
Does 3D right ventricular global longitudinal strain (GLS) assessed by intraoperative TEE predict adverse postoperative outcomes in patients undergoing cardiac surgery?
Does 3D right ventricular global longitudinal strain (GLS) assessed by intraoperative TEE predict adverse postoperative outcomes in patients undergoing cardiac surgery?
Intraoperative 3D transesophageal echocardiography assessment of right ventricular global longitudinal strain provides independent prognostic value for predicting adverse outcomes after cardiac surgery.
May enhance perioperative risk stratification in cardiac surgery; leaves open whether 3D RV mechanics integration improves outcomes.
Risk stratification for cardiac surgery is a cornerstone of perioperative management. While the prognostic impact of severe right ventricular (RV) dysfunction is well understood, the added value of the RV mechanical pattern regarding risk prediction remains unknown. We sought to prospectively validate the predictive value of 3D RV mechanics for adverse perioperative outcomes. The clinical and echocardiographic parameters of 439 retrospectively selected patients who underwent various types of cardiac surgery and 3D transesophageal echocardiography were investigated to determine their associations with a composite endpoint of an unfavorable postoperative outcome. Tricuspid regurgitation, 2D RV strains, and 3D measures of left ventricular (LV) and RV function were associated with the composite endpoint. Multivariable logistic regression models revealed that only tricuspid regurgitation, LV ejection fraction and 3D RV global longitudinal strain (GLS) were independently associated with the endpoint. By applying the model to the data of 128 prospectively enrolled patients, only 3D RV GLS remained an independent predictor. A RV GLS cutoff of -17.4% was found to be associated with a 3-fold increased risk for adverse outcomes. This led us to conclude that RV longitudinal deformation derived from 3D echocardiography is predictive of adverse outcomes and should be incorporated in perioperative risk stratification.
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Keller et al. (2025) studied this question.
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