Mevalonate kinase deficiency is a multisystemic inflammatory disorder that typically presents before age 5 with febrile attacks, and interleukin-1 antagonists appear to be an effective biological treatment.
No takes yet. Share an insight, caveat, or question.
Encourages early MKD evaluation in children under 5 with recurrent fevers and lymphadenopathy or GI symptoms; leaves open optimal therapy pending controlled data.
Bader‐Meunier et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: