Why the study?
Does decreased red blood cell deformability alter wall shear stress and oscillatory shear index in a human carotid artery bifurcation model?
Population
Computational model of human carotid artery bifurcation based on in vivo ultrasound data from a healthy…
Comparison
Simulated decreased red blood cell deformability… vs Simulated normal RBC deformability and Newtonian…
Design
Preclinical
Authors
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May alter carotid bifurcation hemodynamics with impaired RBCs; extends viscosity modeling but leaves clinical relevance open.
Does decreased red blood cell deformability alter wall shear stress and oscillatory shear index in a human carotid artery bifurcation model?
Computational modeling demonstrates that impaired red blood cell deformability alters carotid artery hemodynamics by decreasing regions of low wall shear stress and high oscillatory shear index.
Urevc et al. (2016) studied this question.
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