The purpose of this paper was to investigate the immediate effects of CO2 laser radiation on soft tissue. The morphological changes were studied with gross observations, light microscopy, scanning electron microscopy and were related to the results of thermal measurements . The events which take place during the irradiation were viewed with ultra high speed photography. Air-borne tisssue particles were investigated with cytosmear test and tissue culture. Based upon the various observations, the following conclusions were drawn. The immediate effects of CO2 laser irradiation consit of two factors : physio-mechanical factor and physio-chemical factor. And the nature of the laser injury, in soft tissue, make laser surgery a practical and satisfactory method of controlled tissue removal.
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MIHASHI et al. (1980) studied this question.