Population
Adult transgenic mice
Comparison
Kainic acid-induced limbic seizures vs Baseline/control
Design
Preclinical
Follow-up
up to 24 hours post-seizure
Authors
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Seizure-regulated Lmo expression should not change practice; hypothesis-generating for roles in hippocampal plasticity.
Lmo1, Lmo2, and Lmo3 are expressed in the adult mammalian CNS in a cell type-specific manner and are differentially regulated by neuronal activity.
Hinks et al. (1997) studied this question.
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