Detection and Quantification of Pro-Inflammatory Cytokine in Sera and Urine of Sudanese Patients Infected with Schistosoma Haematobium

Human infections with Schistosomiasis and other helminths induce strange immune responses which are characterised by the production of Th1 and Th2 cytokines. One hundred and thirty sera and urine were collected from patients with urinary schistosomiasis in two villages south Elduiem (Sudan). The disease were confirmed by finding Schistosoma haematobium eggs in urine using syringe filtration techniques. 70 individuals who were Schistosoma haematobium negative included in the study as controls 42 from endemic area and 28 from nonendemic area were tested IFNγ and IL 2 were found in urine and sera. There are a positive association between the production of cytokine and intensity of the infection. They are low intensity in control of endemic area which can be used for early detection of the disease in endemic area.