Why the study?
Does nifedipine inhibit serotonin-, phenylephrine-, and potassium-induced contractions in canine basilar and femoral arteries?
Population
Canine basilar and femoral arteries (in vitro experiments)
Design
Preclinical
Authors
Loading...
Does not support clinical translation; leaves open cerebrovascular selectivity in humans.
Does nifedipine inhibit serotonin-, phenylephrine-, and potassium-induced contractions in canine basilar and femoral arteries?
Nifedipine demonstrates a relatively selective inhibitory effect on contractions of the basilar artery compared to the femoral artery in canine models.
Allen et al. (1979) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: