Why the study?
Does duloxetine 60 mg daily prevent relapse in adult out-patients with major depressive disorder?
Population
278 adult out-patients with major depressive disorder who previously responded to 12 weeks of duloxetine 60…
Comparison
Duloxetine 60 mg daily for 26 weeks vs Placebo for 26 weeks
Design
RCT, Randomised to duloxetine or placebo
Follow-up
26 weeks
Authors
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Supports continuation duloxetine 60 mg to prevent MDD relapse; confirms SNRI efficacy for outpatient maintenance therapy.
Does duloxetine 60 mg daily prevent relapse in adult out-patients with major depressive disorder?
Duloxetine 60 mg daily is effective in preventing relapse of major depressive disorder during continuation treatment.
Pérahia et al. (2006) studied this question.
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