Why the study?
Do vasoactive amines modulate actin cables and surface area in cultured bovine endothelium?
Population
Cultured bovine aortic endothelial cells
Comparison
Vasoactive amines at 10M concentrations vs Controls (untreated cells)
Design
Preclinical
Authors
Loading...
Should not alter clinical practice; leaves open in vivo roles for amines in endothelial barrier integrity.
Do vasoactive amines modulate actin cables and surface area in cultured bovine endothelium?
Serotonin and norepinephrine increase actin cables and surface area in cultured bovine endothelial cells, suggesting a role in maintaining endothelial barrier function.
Welles et al. (1985) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: