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AbstractSerum protein concentration, colloid‐osmotic pressure and plasma volume have been determined in fourteen patients suffering from multiple myeloma. A positive correlation was found between gamma globulin and plasma volume (r= 0.74;p< 0.0005). The colloid‐osmotic pressure was found to be relatively high, eight out of 20 recordings ranging above 46 cm of water. It is claimed that the relationship between gamma globulin and plasma volume depends on the plasma‐expanding effect of gamma globulin. Parallels are drawn to experimental hyperglobulinaemia.
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Bjørneboe et al. (1969) studied this question.
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