What is the clinical evidence from this study?

Study design: Cross-Sectional. Population: Diabetic ketoacidosis (n=54). Intervention: Newly diagnosed diabetic ketoacidosis. Primary outcome: Prevalence of newly diagnosed diabetic ketoacidosis.

What does this research mean for the field?

Newly diagnosed diabetic ketoacidosis accounts for 17.1% of diabetes admissions in a Dakar hospital setting and carries a favorable prognosis with low mortality when managed with continuous intravenous insulin therapy. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the prevalence, diagnostic features, and clinical outcomes of inaugural diabetic ketoacidosis in hospitalized patients.

January 1, 2025Open Journal of Endocrine and Metabolic DiseasesOpen Access

Diagnostic and Evolutionary Aspects of Inaugural Diabetic Ketoacidosis in the Dakar Hospital Setting: A Descriptive and Analytical Cross-Sectional Study in the Endocrinology-Metabolism-Nutrition Department of CHN de Pikine

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Key result

Newly diagnosed diabetic ketoacidosis affects ~17% of patients, resolving in roughly 35 hours.

n=54

Population

54 diabetic patients hospitalized for newly diagnosed diabetic ketoacidosis in the Endocrinology-Metabolism…

Design

Cross-sectional

Follow-up

mean duration of hospitalization 7.6 days

Authors

SSSokhna Awa Balla SallCheikh Anta Diop University NNNafy NdiayeCentre Hospitalier National Universitaire de Fann NDNgoné Diaba DiackCentre Hospitalier National Universitaire de Fann

Discussion

Member takes

Implication

In a Dakar hospital setting, newly diagnosed diabetic ketoacidosis has a prevalence of 17.1% among hospitalized diabetic patients and a generally favorable prognosis with continuous intravenous insulin therapy.

Key Points

To evaluate the prevalence, diagnostic features, and clinical outcomes of inaugural diabetic ketoacidosis in hospitalized patients.
Conducted a descriptive and analytical cross-sectional study from January 1, 2020, to January 31, 2021, at the Pikine National Hospital Center in Dakar.
Enrolled N=54 patients hospitalized with newly diagnosed diabetic ketoacidosis receiving continuous intravenous regular insulin therapy via syringe pump.
Inaugural diabetic ketoacidosis prevalence was 17.1%, presenting with a mean capillary blood glucose of 3.43 g/L, mean HbA1c of 12.2%, and infection as the precipitating cause in 50% of cases.
Diabetes subtypes among patients comprised type 2 diabetes (31 cases), type 1b diabetes (12 cases), type 1 diabetes (9 cases), and corticosteroid-induced diabetes (2 cases).
Ketosis resolved in a mean of 34.6 hours with an average total regular insulin dose of 442.3 IU; 51 patients survived to discharge after an average hospital stay of 7.6 days, and one patient died.

Study Design

Type

Cross-Sectional (n=54)

Multicenter

Structured PICO

Population

54 patients hospitalized for newly diagnosed diabetic ketoacidosis at a single center in Dakar, Senegal.

Exposure

Continuous intravenous insulin therapy via a syringe pump

Outcome

Prevalence, diagnostic characteristics, and outcomes (time to ketosis resolution, duration of hospitalization, mortality) of newly diagnosed diabetic ketoacidosis

Cite This Study

Sall et al. (2025) conducted a cross-sectional in Diabetic ketoacidosis (n=54). Newly diagnosed diabetic ketoacidosis was evaluated on Prevalence of newly diagnosed diabetic ketoacidosis. The prevalence of newly diagnosed diabetic ketoacidosis in the facility was 17.1%, with a mean time to ketosis resolution of 34.6 hours and 1 death among 54 patients.

synapsesocial.com/papers/6a90e9695730a89ab2cae8a7 https://doi.org/10.4236/ojemd.2025.151002

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Diagnostic and Evolutionary Aspects of Inaugural Diabetic Ketoacidosis in the Dakar Hospital Setting: A Descriptive and Analytical Cross-Sectional Study in the Endocrinology-Metabolism-Nutrition Department of CHN de Pikine

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

Diagnostic and Evolutionary Aspects of Inaugural Diabetic Ketoacidosis in the Dakar Hospital Setting: A Descriptive and Analytical Cross-Sectional Study in the Endocrinology-Metabolism-Nutrition Department of CHN de Pikine

Discussion

Member takes

Implication

Key Points

Study Design

Structured PICO

Cite This Study

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