Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
April 23, 2014Anesthesia & Analgesia

Bispectral Index, Sedation, Spinal Anesthesia and Mortality

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does light sedation compared to deep sedation reduce 1-year mortality in elderly patients undergoing emergency hip fracture surgery under spinal anesthesia?

Population

114 patients aged ≥65 years undergoing emergency hip fracture surgery under spinal anesthesia, with a median…

Comparison

Light sedation during spinal anesthesia… vs Deep sedation during spinal anesthesia…

Design

Editorial, Patients were randomized to either BIS level.

Follow-up

1 year

Authors

SMStephen MannionTrinity College DublinPLPeter LeeFlorida State University

Discussion

Loading...

Member takes

Implication

This editorial highlights evidence that lighter sedation during spinal anesthesia for emergency hip fracture surgery in elderly patients with comorbidities significantly reduces 1-year mortality compared to deep sedation.

Structured PICO

Does light sedation compared to deep sedation reduce 1-year mortality in elderly patients undergoing emergency hip fracture surgery under spinal anesthesia?

P
Population
114 patients aged ≥65 years (mean age 81.7 years) undergoing emergency hip fracture surgery under spinal anesthesia, with a median ASA physical status of III.
I
Intervention
Light sedation (Bispectral Index [BIS] level >80) during spinal anesthesia, receiving a median of 1.3 mg/kg propofol and 10 mg midazolam.
C
Comparator
Deep sedation (Bispectral Index [BIS] level approximately 50) during spinal anesthesia, receiving a median of 8.1 mg/kg propofol and 2 mg midazolam.
O
Outcome
1-year mortalityhard clinical

This editorial highlights evidence that lighter sedation during spinal anesthesia for emergency hip fracture surgery in elderly patients with comorbidities significantly reduces 1-year mortality compared to deep sedation.

Limitations

  • Original randomization was designed to compare the incidence of delirium, not mortality.

Cite This Study

Mannion et al. (2014) studied this question.

synapsesocial.com/papers/6a90ea9d8b76b10fb073cdffhttps://doi.org/10.1213/ane.0000000000000205
View Full Paper
Ask AI
Bookmark
Share