A Task Group of the International Commission on Radiological Protection (ICRP Publication 11, 1968) reviewed the tissues at risk of malignant transformation from the deposition of radioactive material in bone. It noted specially: (1) the haemopoietic bone marrow with respect to leukaemia; (2) the osteoprogenitive tissues of endosteum with respect to osteosarcoma; and (3) certain epithelia in cranial air sinuses, outside bone itself but closely adherent to it, and subject to carcinoma.
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Loutit et al. (1971) studied this question.
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