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May 1, 1961Journal of Bone and Joint Surgery - British Volume

Osteogenic Sarcoma

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Why the study?

Does histological grading based on mitotic activity correlate with survival in patients with osteogenic sarcoma?

Population

88 patients with osteogenic sarcomata

Design

Cohort

Follow-up

5 years

Authors

CPC. H. G. PriceRoche (United Kingdom)

Discussion

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Implication

Mitotic grading may stratify prognosis in osteogenic sarcoma; leaves open prospective validation before clinical use.

Structured PICO

Does histological grading based on mitotic activity correlate with survival in patients with osteogenic sarcoma?

P
Population
88 patients with osteogenic sarcomata
I
Intervention
Histological grading based on mitotic activity (Grade I, II, III)
O
Outcome
Survival in months and 5-year survival ratehard clinical

Histological grading based on mitotic activity strongly correlates with survival in patients with osteogenic sarcoma, providing a useful prognostic tool.

Cite This Study

C. H. G. Price (1961) studied this question.

synapsesocial.com/papers/6a8982145c4c6b099dec7296https://doi.org/10.1302/0301-620x.43b2.300
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Survival, prognosis, and therapeutic response in osteogenic sarcoma. The memorial hospital experience1992 · 283 citations
  2. 2Stage IIB Osteogenic Sarcoma1991 · 38 citations
  3. 3Does synovial sarcoma grade predict oncologic outcomes, and does a low‐grade variant exist?2022 · 4 citations
  4. 4Osteogenic sarcoma. A study of one hundred and thirty cases1975 · 31 citations
  5. 5Osteosarcoma:A Multifactorial Clinical and Histopathological Study with Special Regard to Therapy and Survival1978 · 29 citations