January 1, 1978Acta Orthopaedica ScandinavicaOpen Access

Osteosarcoma:A Multifactorial Clinical and Histopathological Study with Special Regard to Therapy and Survival

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Why the study?

How do different surgical approaches affect the 5-year survival rate in patients with genuine osteosarcoma?

Population

153 unequivocal cases of genuine osteosarcoma recorded in the Swedish Cancer Registry. Excluded: parosteal…

Design

Cohort

Follow-up

5 years

Authors

SLSven‐Erik LarssonLinköping University Hospital RLRonny LorentzonUmeå University HWHans WedrènAleris Hälsocentral Bollnäs

Discussion

Member takes

Implication

Radical surgery was associated with higher survival in osteosarcoma; leaves open relevance with modern multimodal therapy.

Structured PICO

How do different surgical approaches affect the 5-year survival rate in patients with genuine osteosarcoma?

Population

153 unequivocal cases of genuine osteosarcoma recorded in the Swedish Cancer Registry (1958-1968). Excluded: parosteal osteosarcoma, soft-tissue osteosarcoma, and osteosarcoma secondary to Paget's disease of bone.

Intervention

Various surgical treatments (amputation above the joint proximal to the involved skeletal part, amputation on the involved skeletal part, local extirpation, or non-radical removal)

Outcome

5-year survival ratehard clinical

More radical surgical approaches, such as amputation above the proximal joint, were associated with higher 5-year survival rates in patients with osteosarcoma.

Cite This Study

Larsson et al. (1978) studied this question.

synapsesocial.com/papers/6a90ec641cb9ea1c853e778a https://doi.org/10.3109/17453677808993240

View Full Paper

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January 1, 1978Acta Orthopaedica ScandinavicaOpen Access

Osteosarcoma:A Multifactorial Clinical and Histopathological Study with Special Regard to Therapy and Survival

View Full Paper

Ask AI

Bookmark

Why the study?

How do different surgical approaches affect the 5-year survival rate in patients with genuine osteosarcoma?

Population

153 unequivocal cases of genuine osteosarcoma recorded in the Swedish Cancer Registry. Excluded: parosteal…

Design

Cohort

Follow-up

5 years

Authors

SLSven‐Erik LarssonLinköping University Hospital RLRonny LorentzonUmeå University HWHans WedrènAleris Hälsocentral Bollnäs

Discussion

Member takes

Implication

Radical surgery was associated with higher survival in osteosarcoma; leaves open relevance with modern multimodal therapy.

Structured PICO

How do different surgical approaches affect the 5-year survival rate in patients with genuine osteosarcoma?

Population

Intervention

Various surgical treatments (amputation above the joint proximal to the involved skeletal part, amputation on the involved skeletal part, local extirpation, or non-radical removal)

Outcome

5-year survival ratehard clinical

More radical surgical approaches, such as amputation above the proximal joint, were associated with higher 5-year survival rates in patients with osteosarcoma.

Cite This Study

Larsson et al. (1978) studied this question.

synapsesocial.com/papers/6a90ec641cb9ea1c853e778a https://doi.org/10.3109/17453677808993240

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

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