May 1, 1977American Journal of Clinical Pathology

Primary Osteosarcoma of Bone: A Clinicopathologic Investigation of 243 Cases, with Necropsy Studies in 54

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Population

243 patients with pathologically verified primary osteosarcomas of bone treated at The University of Texas…

Design

Cohort

Follow-up

5 years

Authors

GUGonzalo Uribe-BoteroThe University of Texas MD Anderson Cancer Center WRWilliam O. RussellAmerican Cancer Society WSWataru W. SutowAmerican Cancer Society

Discussion

Member takes

Implication

Historical cohort confirms poor pre-adjuvant osteosarcoma survival; leaves open impact of contemporary multimodal regimens.

Structured PICO

Population

243 patients with pathologically verified primary osteosarcomas of bone treated at The University of Texas System Cancer Center, M. D. Anderson Hospital and Tumor Institute over a 24-year period. 76.5% of cases occurred in patients less than 25 years old.

Intervention

Surgery, irradiation, and chemotherapy (prior to the use of adjuvant chemotherapy)

Outcome

Survival (3-year and 5-year survival rates)hard clinical

Prior to the use of adjuvant chemotherapy, primary osteosarcoma of bone had a poor prognosis with a 5-year survival rate of only 12.6%.

Cite This Study

Uribe-Botero et al. (1977) studied this question.

synapsesocial.com/papers/6a7e5a851fdb7ee677c76d69 https://doi.org/10.1093/ajcp/67.5.427

View Full Paper

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May 1, 1977American Journal of Clinical Pathology

Primary Osteosarcoma of Bone: A Clinicopathologic Investigation of 243 Cases, with Necropsy Studies in 54

View Full Paper

Ask AI

Bookmark

Population

243 patients with pathologically verified primary osteosarcomas of bone treated at The University of Texas…

Design

Cohort

Follow-up

5 years

Authors

GUGonzalo Uribe-BoteroThe University of Texas MD Anderson Cancer Center WRWilliam O. RussellAmerican Cancer Society WSWataru W. SutowAmerican Cancer Society

Discussion

Member takes

Implication

Historical cohort confirms poor pre-adjuvant osteosarcoma survival; leaves open impact of contemporary multimodal regimens.

Structured PICO

Population

Intervention

Surgery, irradiation, and chemotherapy (prior to the use of adjuvant chemotherapy)

Outcome

Survival (3-year and 5-year survival rates)hard clinical

Prior to the use of adjuvant chemotherapy, primary osteosarcoma of bone had a poor prognosis with a 5-year survival rate of only 12.6%.

Cite This Study

Uribe-Botero et al. (1977) studied this question.

synapsesocial.com/papers/6a7e5a851fdb7ee677c76d69 https://doi.org/10.1093/ajcp/67.5.427

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