Why the study?
Supraclavicular block provides excellent postoperative outcomes for upper limb surgeries, but the efficacy of long-acting bupivacaine is altered by co-administered additives.
Do additives (lidocaine, sodium bicarbonate, dexamethasone) improve the efficacy of 0.5% bupivacaine in supraclavicular block for upper limb surgeries?
Do additives (lidocaine, sodium bicarbonate, dexamethasone) improve the efficacy of 0.5% bupivacaine in supraclavicular block for upper limb surgeries?
In supraclavicular blocks, adding lidocaine to bupivacaine shortens block onset time, while adding dexamethasone significantly prolongs the duration of analgesia.
Answers are grounded in this paper and cite their sources.
Case report on SCB additives warrants caution before adoption; leaves open need for RCTs to assess efficacy and safety.
Introduction: Supraclavicular block (SCB) is associated with excellent postoperative patient outcomes for upper limb surgeries. Bupivacainei is a longacting regional anaesthetic, efficacy of which is altered with the co-administration of additives. Aim: Aim of the study was to assess the efficacy of supraclavicular block with 0.5% bupivacaine compared to co-administration of additives and the associated complications. Method: Following ethical clearance and informed written consent, over 5 months from July 2020, 152 adult patients at Teaching Hospital Anuradhapura Sri Lanka undergoing upper limb surgeries were divided into 4 groups & prospectively followed-up. All groups received 0.5% of Bupivacaine while additives 2% Lidocaine, 8.4% sodium bicarbonate & 8 mg Dexamethasone were added to the other 3 groups. Sensory and Motor block onset time, duration of post-block analgesia, acute and late complications and patient satisfaction were noted. Data was analysed using descriptive statistics & ANOVA, using SPSS V.25. Results: Successful surgical anesthesia was achieved in all patients with 0 cases of long-term neurological complications with 94% patient satisfaction. The motor & sensory block onset time & post block analgesia duration respectively for Lidocaine (9.74 min, 9.74 min & 7.07 h), Bicarbonate (12.89 min, 16.32 min & 12.09 h), dexamethasone (19.34 min, 17.24 min & 20.87 h) & Bupivacaine were (20.39 min, 18.42 min & 13.15 h). Conclusion: The differences between bupivacaine and lidocaine groups for sensory & motor block onset times & between Bupivacaine & dexamethasone groups for post-block analgesia duration were statistically significant (p < 0.001). Supraclavicular block has minimal associated complications & additives Lidocaine shortens the onset of anaesthesia and the duration of analgesia while dexamethasone prolongs the duration of analgesia significantly.
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Minura Hapugoda (2021) studied this question.
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