Why the study?
Recent studies demonstrated inflammation's role in atherosclerotic cardiovascular disease, prompting investigation into the rationale and recent outcome trials of colchicine in atherosclerosis.
Does colchicine reduce cardiovascular events in patients with atherosclerosis?
Does colchicine reduce cardiovascular events in patients with atherosclerosis?
Colchicine reduces atherosclerotic cardiovascular events in patients with acute and chronic coronary syndromes, though it does not appear to reduce all-cause mortality.
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Divergent colchicine trial results in CAD warrant caution in broad use; review of design differences leaves open explanations for inconsistencies.
Banach et al. (2021) studied this question.
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