Why the study?
Do newer antidepressants prevent relapse and recurrence of depression better than older antidepressants?
Population
Patients with depression
Comparison
Newer antidepressants vs Older antidepressants
Design
Review
Authors
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High recurrence risk supports maintenance consideration; leaves open whether newer antidepressants outperform older agents for relapse prevention.
Do newer antidepressants prevent relapse and recurrence of depression better than older antidepressants?
Long-term observational data highlight the high risk of depression recurrence and the critical need for continuation and maintenance therapy.
Jeffrey G. Edwards (1997) studied this question.
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