Population
Perfused rainbow trout heart model
Comparison
Catecholamines and extracellular calcium vs Control conditions and acidotic conditions…
Design
Preclinical
Authors
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Should not change clinical practice; hypothesis-generating for catecholamine rescue of acidotic contractility in mammalian models.
In a perfused rainbow trout heart model, catecholamines and extracellular calcium modulate cardiac contractility and can partially rescue the negative inotropic and chronotropic effects of extracellular acidosis.
Farrell et al. (1986) studied this question.
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