Why the study?
Is platelet-activating factor acetylhydrolase activity in plasma lipoproteins altered in patients with ischemic stroke compared to healthy controls?
Population
64 individuals, comprising 33 patients with cerebral thrombosis and 31 age-matched healthy control subjects.
Design
Case-control
Authors
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Higher LDL PAF-AH activity was associated with ischemic stroke; leaves open causal role and clinical relevance.
Is platelet-activating factor acetylhydrolase activity in plasma lipoproteins altered in patients with ischemic stroke compared to healthy controls?
Patients with ischemic stroke have increased platelet-activating factor acetylhydrolase activity bound to low-density lipoprotein, potentially as an adaptation to augmented generation of platelet-activating factor.
Satoh et al. (1992) studied this question.
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