Population
Epithelial cells undergoing Snail1-induced epithelial-mesenchymal transition and human tumors with low…
Comparison
Ectopic overexpression of a natural antisense… vs Control epithelial cells
Design
Preclinical
Authors
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NAT-Zeb2 axis may regulate EMT in disease; hypothesis-generating and should not yet change practice.
The study identifies a natural antisense transcript that activates Zeb2 expression by preventing intron splicing, thereby regulating E-cadherin expression during epithelial-mesenchymal transition.
Beltrán et al. (2008) studied this question.
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