Population
BSVS mice and C57BL/6J mice
Design
Preclinical
Authors
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Alerts to strain-specific immune biases in infection models; leaves open translation to human thymus-dependent responses.
BSVS mice demonstrate a specific generalized deficiency in thymus-dependent IgG immune responses, likely related to selective breeding for infection susceptibility.
Briles et al. (1979) studied this question.
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