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July 1, 1972Circulation

Left Ventricular Papillary Muscles

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Authors

WRWilliam C. RobertsGeneral CardiologyLCLawrence S. CohenCosmos Corporation (United States)

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Implication

Pathological review demonstrates vulnerability of left ventricular papillary muscles to ischemia from arterial narrowing, highlighting their value as anatomical markers of myocardial damage.

Key Points

  • Review the blood perfusion patterns, ischemic sensitivity, and various pathological disorders affecting the papillary muscles of the left ventricle.
  • Synthesized pathological and anatomical observations regarding coronary arterial perfusion and myocardial supply gradients.
  • Evaluated diverse etiologies of necrosis, fibrosis, and malformations across ischemic, infiltrative, and congenital cardiac conditions.
  • Left ventricular papillary muscles represent the final myocardial zones perfused by coronary arterial blood, rendering them primary anatomical markers of myocardial ischemia.
  • The posteromedial papillary muscle exhibits a higher vulnerability to necrosis and fibrosis than the anterolateral muscle due to a less redundant blood supply, predominantly caused by coronary luminal narrowing.
  • Non-coronary etiologies including left ventricular outflow tract obstruction, cardiomyopathies, and infiltrative diseases produce comparable lesions, while adjacent free wall injury can clinically mimic papillary muscle dysfunction.

Cite This Study

Roberts et al. (1972) studied this question.

synapsesocial.com/papers/6a910dc351c11e6b603605d9https://doi.org/10.1161/01.cir.46.1.138
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