What question did this study set out to answer?

To evaluate the clinical presentation, time delays, therapeutic management, and in-hospital outcomes of patients admitted with acute coronary syndrome at a tertiary care center in eastern Nepal.

April 11, 2011Swiss Medical WeeklyOpen Access

Presentation and outcomes of patients with acute coronary syndromes in eastern Nepal

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Population

153 consecutive patients admitted with acute coronary syndrome to a tertiary care centre in eastern Nepal.

Design

Cohort

Follow-up

in-hospital

Authors

NSN ShreshtaB.P. Koirala Institute of Health Sciences SBS BasnetIndiana University Health RBRabin BhandariB.P. Koirala Institute of Health Sciences

Discussion

Member takes

Implication

Highlights urgent need to address delays and thrombolysis access in resource-limited ACS settings; leaves open whether interventions improve survival.

Key Points

To evaluate the clinical presentation, time delays, therapeutic management, and in-hospital outcomes of patients admitted with acute coronary syndrome at a tertiary care center in eastern Nepal.
Conducted an observational study of 153 consecutive patients admitted with acute coronary syndrome between January 1 and December 31, 2008, at a tertiary care center in eastern Nepal.
Assessed patient diagnostic categories (STEMI, NSTEMI, and unstable angina), literacy, time from symptom onset to presentation, delivery of thrombolytic therapy, and in-hospital mortality.
Among 153 admitted patients, 38% had STEMI (n=58), 18% had NSTEMI (n=28), and 44% had unstable angina (n=67).
Only 40% of STEMI patients arrived within 12 hours of symptom onset, 33% presented after 2 days or more, and only 53% of patients eligible for broadened 24-hour streptokinase thrombolysis received it due to financial barriers.
In-hospital mortality was 14% across all patients with acute coronary syndrome and 17% among patients with STEMI.

Structured PICO

Population

153 consecutive patients admitted with acute coronary syndrome (ACS) (58 STEMI, 28 NSTEMI, 67 unstable angina) to a tertiary care centre in eastern Nepal.

Outcome

In-hospital outcomes including mortality, time delays, and treatment receivedhard clinical

Patients with ACS in eastern Nepal face significant delays in presentation and financial barriers to optimal medical management, resulting in high in-hospital mortality.

Cite This Study

Shreshta et al. (2011) studied this question.

synapsesocial.com/papers/6a9111d5efab70d99b73e1db https://doi.org/10.4414/smw.2011.13174

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Implication

Highlights urgent need to address delays and thrombolysis access in resource-limited ACS settings; leaves open whether interventions improve survival.

Presentation and outcomes of patients with acute coronary syndromes in eastern Nepal

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Presentation and outcomes of patients with acute coronary syndromes in eastern Nepal

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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Also Consider