January 22, 1982Quarterly Journal of Experimental Physiology

The Response in Efferent Cardiac Sympathetic Nerves to Stimulation of Atrial Receptors, Carotid Sinus Baroreceptors and Carotid Chemoreceptors

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Population

Dogs anaesthetized with chloralose

Comparison

Distension of small balloons in the pulmonary… vs Control activity / efferent cardiac nerves which…

Design

Preclinical

Authors

RLR. J. LindenLeeds General Infirmary DMD. A. S. G. MaryUniversity of Pittsburgh DWD. WeatherillUniversity of California, Los Angeles

Discussion

Member takes

Implication

Distinguishes atrial-specific sympathetic efferents in animal models; leaves open translation to human autonomic regulation or targeted therapies.

Structured PICO

Population

Dogs anaesthetized with chloralose

Intervention

Distension of small balloons in the pulmonary vein-atrial junctions, changes in carotid sinus pressure (8 to 30 kPa), changes in blood perfusing the sinuses from arterial to venous, and stimulation of the cutaneous branch of the left radial nerve

Comparator

Control activity / efferent cardiac nerves which did not respond to the distension of the balloons

Outcome

Reflex increase in activity in efferent cardiac sympathetic nerve fibressurrogate

This preclinical study demonstrates that efferent cardiac sympathetic nerve fibers responding to atrial receptors are functionally distinct from those responding to carotid or somatic stimulation.

Cite This Study

Linden et al. (1982) studied this question.

synapsesocial.com/papers/6a9111e41a4f16208192d8ca https://doi.org/10.1113/expphysiol.1982.sp002609

View Full Paper

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Implication

Distinguishes atrial-specific sympathetic efferents in animal models; leaves open translation to human autonomic regulation or targeted therapies.

The Response in Efferent Cardiac Sympathetic Nerves to Stimulation of Atrial Receptors, Carotid Sinus Baroreceptors and Carotid Chemoreceptors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The Response in Efferent Cardiac Sympathetic Nerves to Stimulation of Atrial Receptors, Carotid Sinus Baroreceptors and Carotid Chemoreceptors

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider