Endocardial fibro-elastosis, mitral incompetence, and coarctation of abdominal aorta.

Congenital mitral incompetence has been only rarely reported as an isolated lesion (Miller, Brown, and Swan, 1964), but may occur as a result of endo- cardial fibro-elastosis, which is also commonly associated with other anatomical abnormalities, of which coarctation of the aorta is one. The associa- tion of congenital mitral incompetence and coarcta- tion of the abdominal aorta has not been reported previously, so we are presenting a family of 3 sibs who had this association of defects. The patho- logical findings are given in some detail, and the pathology of endocardial fibro-elastosis is reviewed.