Experimental study demonstrates targeted fluorescence imaging of HDAC8 in tumor tissue slices, highlighting utility for drug screening and disease diagnosis.
was applied to imaging SH-SY5Y tumor tissue slices to indicate the relative expression level of HDAC8. Therefore, this HDAC8-selective fluorescent probe can be expected for applications in HDAC8-targeted drug screening as well as in pathologic diagnoses.
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Yan et al. (2021) studied this question.
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