Carcinoma of the Colon and Antecedent Epithelium

Throughout the past few decades most cancer research has been directed towards a more thorough understanding of cellular and tissue biology. A considerable portion of these studies have to do with gastrointestinal epithelium, for this epithelium can be readily studied in the laboratory and also has an inherently high replication rate. The material published in the 26 chapters of this book report the techniques, results, and conclusions of 39 different individuals who have pursued these basic studies. At the same time, the book offers a preliminary report on the way such studies may relate to eventual understanding of colonic carcinoma. The book is divided into four parts, each with several reports and a concluding chapter summarizing the relationship of the studies to oncogenesis. The first part deals with knowledge regarding the growth of normal and abnormal colonic epithelium. It includes an analysis of current surgical approaches to colonic carcinoma based