Why the study?
Can mitral annulus displacement measured by two-dimensional speckle tracking echocardiography assess left ventricular longitudinal systolic function in patients with coronary heart disease?
Can mitral annulus displacement measured by two-dimensional speckle tracking echocardiography assess left ventricular longitudinal systolic function in patients with coronary heart disease?
Mitral annulus displacement measured by 2D speckle tracking echocardiography serves as an early and rapid index for assessing left ventricular longitudinal systolic function across different severities of coronary heart disease.
MAD by 2D speckle tracking associates with CHD severity; supports function assessment but leaves open prospective validation and clinical adoption.
AIM: To assess the clinical utility of measuring mitral annulus displacement (MAD) by two-dimensional speckle tracking for the rapid evaluation of left ventricular longitudinal systolic function in patients with coronary heart disease (CHD). METHODS: Left ventricular longitudinal systolic function was evaluated by MAD using speckle tracking echocardiography in 30 healthy volunteers (controls) as well as in 30 patients with mild, 30 patients with moderate, and 30 patients with severe CHD. All participants had their apical four-chamber and two-chamber view echocardiographic images recorded. Left ventricular end-diastolic volume, left ventricular end-systolic volume, and left ventricular ejection fraction were calculated by the biplane Simpson method. MAD of interventricular septum (MADsep), left ventricular lateral wall (MADlat), and the middle point of the mitral annulus (MADmid) were measured offline with speckle-tracking echocardiography. MADmid% was defined as MADmid divided by left ventricular end-diastolic diameter. RESULTS: MADmid% was 16.9 ± 1.9, 11.8 ± 3.2, 11.8 ± 2.9, and 10.3 ± 3.6, respectively, in controls and in patients with mild, moderate, and severe CHD. All MAD indexes were lower in patients with moderate or severe CHD than in controls or patients with mild CHD. CONCLUSIONS: MAD is an early and rapid index for the assessment of left ventricular longitudinal systolic function in patients with different degrees of coronary artery disease.
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Thapa et al. (2014) studied this question.
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