Evaluation of left ventricular systolic function by tissue motion annular displacement of the mitral valve derived by speckle-tracking echocardiography in patients with coronary artery disease

Objectives: Evaluation of the left ventricular systolic function using tissue motion annular displacement of mitral valve derived by speckle - tracking echocardiography and the correlation between mitral valve annular displacement and echocardiographic parameters for left ventricular systolic function in patients with coronary artery disease. Methods: Descriptive cross - sectional study on 106 patients with coronary artery disease and 106 controls, at Hue University of Medicine and Pharmacy Hospital, from 3/2019 - 10/2021. The study population meet all inclusion criteria according to research objectives. Mitral valve annular displacement derived by speckle - tracking echocardiography was acquired and analyzed offline with QLAB 13. Results: Median age was 66.09 ± 13.25 years and 66.7% was woman. Mitral valve annular displacement derived by speckle - tracking echocardiography in patients with coronary artery disease decreased statistically significant when comparing to control group (p < 0.01). This index which was strongly correlated not only with left ventricular ejection fraction on 2D (r = 0.706) but also with peak mitral annular systolic velocity (S’ velocity) by tissue Doppler (r = 0.882). It was a favorable correlation with maximum mitral annular systolic displacement on M - mode (r = 0.419), but was not correlated with the location, degree, and number of coronary stenosis. Conclusions: Tissue motion annular displacement of the mitral valve derived by speckle - tracking echocardiography is a simple, rapid and endothelium - independent parameter that supports the left ventricular ejection fraction parameter in the evaluation of left ventricular systolic function when poor endocardial visualization.