Combination chemotherapy and interleukin-2 successfully induced complete remission in a patient with vaginal angiosarcoma.
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Should not change practice in vaginal angiosarcoma; leaves open IL-2 combinations as hypothesis-generating for this rare tumor.
We report a case of angiosarcoma of the vagina in a 61-year-old woman who had undergone radical hysterectomy and pelvic irradiation for uterine cervical adenocarcinoma 14 years previously. Combination chemotherapy (cyclophosphamide, vincristine, doxorubicin and dacarbazine) and interleukin-2 induced complete remission of the tumor. The patient remained free from disease for 15 months.
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Morimura et al. (2001) studied this question.
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