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December 6, 1994Proceedings of the National Academy of SciencesOpen Access

Targeted gene replacement demonstrates that myristoyl-CoA: protein N-myristoyltransferase is essential for viability of Cryptococcus neoformans.

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Authors

JLJennifer K. LodgeDuke UniversityEJEmily Jackson-MachelskiMonsanto (United States)DTDena L. ToffalettiDuke University

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Lodge et al. (1994) studied this question.

synapsesocial.com/papers/6a911592f61bbdbd5ac1b737https://doi.org/10.1073/pnas.91.25.12008
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Suppressors of nmtl-181, a conditional lethal allele of the Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase gene, reveal proteins involved in regulating protein N-myristoylation.1994 · 21 citations
  2. 2ADP Ribosylation Factor Is an Essential Protein in <i>Saccharomyces cerevisiae</i> and Is Encoded by Two Genes1990 · 63 citations
  3. 3Isolation of the URA5 gene from Cryptococcus neoformans var. neoformans and its use as a selective marker for transformation.1990 · 201 citations
  4. 4Isolation of the URA5 Gene from Cryptococcus neoformans var. neoformans and Its Use as a Selective Marker for Transformation1990 · 66 citations
  5. 5Mutations of human myristoyl-CoA:protein N-myristoyltransferase cause temperature-sensitive myristic acid auxotrophy in Saccharomyces cerevisiae.1992 · 115 citations