What question did this study set out to answer?

To determine the relative frequency of tapered collagen fibrils across diverse adult, embryonic, and neoplastic human tissues.

December 1, 1952Experimental Biology and Medicine

Occurrence of Tapered Collagen Fibrils from Human Sources with Observations on Mesenchymal Neoplasms.

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Authors

WBWilliam G. BanfieldAmerican Cancer Society

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Implication

Electron microscopy study observes higher frequencies of tapered collagen fibrils in developing and neoplastic tissues, suggesting their presence marks active collagen formation.

Key Points

To determine the relative frequency of tapered collagen fibrils across diverse adult, embryonic, and neoplastic human tissues.
Examined adult human tissues (skin, Achilles tendon, dura, and endometrium) and embryonic tissues (skin and Achilles tendon) under an electron microscope.
Assessed benign and malignant mesenchymal neoplasms using electron microscopy to quantify the occurrence of collagen fibrils with tapered ends.
Collagen fibrils with tapered ends occurred with noticeably greater frequency in tissue sites undergoing active collagen synthesis compared to mature tissues.

Cite This Study

William G. Banfield (1952) studied this question.

synapsesocial.com/papers/6a911c3c780df83b8fe1bb52 https://doi.org/10.3181/00379727-81-19977

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Implication

Electron microscopy study observes higher frequencies of tapered collagen fibrils in developing and neoplastic tissues, suggesting their presence marks active collagen formation.

Occurrence of Tapered Collagen Fibrils from Human Sources with Observations on Mesenchymal Neoplasms.

Discussion

Member takes

Implication

Key Points

Cite This Study

Occurrence of Tapered Collagen Fibrils from Human Sources with Observations on Mesenchymal Neoplasms.

Discussion

Member takes

Implication

Key Points

Cite This Study

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