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Glucagon selectively potentiates an effect of hydrocortisone: when injected into adrenalectoinized rats it increases fourfold the induction by hydrocortisone of tyrosine transaminase, but not of tryptophan pyrrolase. Glucagon alone doubles the basal level of tyrosine transaminase and decreases that of tryptophan pyrrolase. The effects of glucagon on both enzymes resemble those of starvation.
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Greenagard et al. (1966) studied this question.
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